Sample size calculation: Basic principles
نویسندگان
چکیده
منابع مشابه
Sample size calculation: Basic principles
Addressing a sample size is a practical issue that has to be solved during planning and designing stage of the study. The aim of any clinical research is to detect the actual difference between two groups (power) and to provide an estimate of the difference with a reasonable accuracy (precision). Hence, researchers should do a priori estimate of sample size well ahead, before conducting the stu...
متن کاملPrinciples of sample size calculation
In most areas in life, it is difficult to work with populations and hence researchers work with samples. The calculation of the sample size needed depends on the data type and distribution. Elements include consideration of the alpha error, beta error, clinically meaningful difference, and the variability or standard deviation. The final number arrived at should be increased to include a safety...
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This paper discusses the statistical principles, methods, and software programs used to calculate sample size. In addition, it reviews the practical challenges faced in calculating sample size. We show that because of such challenges, statistical calculations often do not provide us with a clear-cut number for the study sample size; rather they suggest a range of reasonable numbers. The paper a...
متن کاملCME Series Sample size calculations: basic principles and common pitfalls
One of the most common requests that statisticians get from investigators are sample size calculations or sample size justifications. The sample size is the number of patients or other experimental units included in a study, and determining the sample size required to answer the research question is one of the first steps in designing a study. Although most statistical textbooks describe techni...
متن کاملSample size calculations: basic principles and common pitfalls.
One of the most common requests that statisticians get from investigators are sample size calculations or sample size justifications. The sample size is the number of patients or other experimental units included in a study, and determining the sample size required to answer the research question is one of the first steps in designing a study. Although most statistical textbooks describe techni...
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ژورنال
عنوان ژورنال: Indian Journal of Anaesthesia
سال: 2016
ISSN: 0019-5049
DOI: 10.4103/0019-5049.190621